Mirava Polyscope
one for all and all for one:
the perfect image
abberior’s MIRAVA® is the first true POLYSCOPE®. It unites four microscopy technologies to cover an unprecedented resolution spectrum, extending over several orders of magnitude from diffraction-limited imaging all the way to true molecular resolution.
Many eyes see more than one: Matrix Imaging
Imaging with MATRIX array detection means resolution beyond the diffraction limit and unsurpassed signal-to-background ratio.
Thick or dense samples with a lot of background become clear and sharp as the MATRIX isolates relevant signal from the rest. This allows you to process and analyze data with much greater confidence and achieve the best results.
Our MATRIX detector consists of 23 individual detector elements. On its own, each one of them is a small pinhole, able to record at the highest diffraction-limited resolution. At the same time, all elements taken together, give you the full signal of a large-area detector. The best out of both worlds, high signal and high resolution in one single shot!
Nobel prize technology from its inventors
MIRAVA STED – 30 years of experience meets attention to detail.
Performing STED microscopy on the MIRAVA means applying top-notch technology for best results. Use gentle STED laser power together with TRUESHARP image boosting for a significant increase in resolution compared to confocal imaging, without stressing the sample. Increase power if you need an even more detailed image and use FLEXPOSURE adaptive illumination to keep the light dose down. Or push it to the max and combine all our STED technologies to reach 20 nm resolution. Whatever you need, with MIRAVA, it’s all just a matter of a few clicks.
Even 3D STED is no more difficult. abberior’s dynamic beam shaper modulates the STED donut and optimally adapts it to different objective lenses.
abberior’s superpowers to master any task.
RAYSHAPE dynamic aberration correction allows you to look deep into complex samples like tissue or whole organisms without compromising on image quality due to aberrations. Using adaptive optics with a deformable mirror, RAYSHAPE puts diverted rays back on track, guaranteeing bright and crisp images from top to bottom – regardless of embedding medium, immersion medium, or specimen.
We established pulsed STED lasers as a gold standard long ago to reduce bleaching and phototoxicity and further reduced these harmful effects with the development of FLEXPOSURE adaptive illumination. With FLEXPOSURE, you are still recording long-term experiments over volumes or many frames, while ordinary always-on-lasers have long bleached the sample to death. Instead of illuminating the specimen with full intensity everywhere, we are gentle to the sample and turn all lasers on and off, shining light only where and when it has an effect and nowhere else.
TIMEBOW lifetime imaging gives time a color. Every fluorescence signal contains lifetime information that travels with the photons from the sample to the detector. TIMEBOW allows you to reveal previously hidden structural details by separating fluorophores emitting in the same spectral channel. This gives you great additional possibilities when it comes to multicolor labeling and imaging. Additionally, TIMEBOW STED exploits the spatial information encoded in the lifetime to increase image resolution.
Add the MATRIX array detector and increase resolution and image quality even further, by using the information that is encoded in the simultaneous recording of 23 images from different angles.
Our wonder weapon is TRUESHARP image boosting. TRUESHARP offers next generation deconvolution you can trust. It removes noise and background signal from your recorded data and strongly enhances resolution, sharpness, and brilliance of your images by incorporating experimentally measured information.
100x sharper than a confocal:
Minflux Imaging
Straightforward, easy, and reliable: unmatched resolution out-of-the-box with MINFLUX.
With the MINFLUX module of the MIRAVA POLYSCOPE, imaging at the molecular level is easier than ever. Set up and control your MINFLUX measurement with just a few clicks, thanks to seamless integration into our sleek LiGHTBOX software.
The MINFLUX hardware is fully integrated into
the MIRAVA system, yielding unmatched robustness and optical quality. It constantly monitors and corrects even subtle, sub-nanometer drifts caused by environmental changes (e.g. ambient temperature), keeping your sample perfectly still for days.
MIRAVA sets the stage for effortless microscopy on the molecular level. Focus on your measurement and let MIRAVA do the MINFLUX.
LiGHTBOX software
it's all about ease of use
Designed for seamless operation and unparalleled in its clear structure, abberior’s LiGHTBOX ensures that even the most advanced imaging technologies are accessible to all users, regardless of their experience. All major settings are just one click away, and the intuitive software design facilitates quick learning, while it grants experts full control over all aspects of their measurement. You can even automate image acquisition and analysis by running Python scripts.
Thanks to LiGHTBOX you can focus on your research because the software handles the tedious tasks on its own, like detection bands, alignment, aberration correction while focusing, Nyquist sampling, focus, exposure settings…
Switching between confocal imaging and MATRIX, STED, or MINFLUX is a matter of seconds. And setting up the measurement doesn’t take much longer, no matter what imaging technique you choose.
LiGHTBOX is the most comprehensive and user-friendly solution for highest imaging demands.