100x sharper than a confocal microscope
100x faster tracking than a camera
Although impactful, previous superresolution methods have failed to achieve resolutions on the length scales of the fluorescent molecules. Harnessing an entirely new and revolutionary localization principle, MINFLUX has finally accomplished this feat. Expect a resolution leap of 10-fold compared to other superresolution methods and 100-fold compared to confocal fluorescence imaging.
MINFLUX is the most precise and most photon-efficient way of localizing fluorescent molecules. With its new MINFLUX system, abberior has produced the first commercial fluorescence microscope that can achieve localization precisions of 1-3 nm (3D) in biological samples on large fields of view (10 x 15 μm). MINFLUX imaging means getting the maximal localization information out of your sample.
MINFLUX tracks molecular movements at frequencies up to 10 kHz, resolving molecular motion every 100 μs. That’s 100 times faster than conventional camera-based methods. Of, course, tracking works in all three dimensions, i.e. along x, y, and z. Due to the low number of photons required for each localization, single molecules can be monitored with unprecedented spatio-temporal resolution (e.g. 28.000 localizations each at 20 nm resolution).
MINFLUX is the fastest way to localize fluorescent molecules. With its revolutionary MINFLUX microscope, abberior is raising the bar for molecular tracking with world-record temporal resolution, opening new doors for life-scientists across all disciplines.
Choose between MINFLUX molecular imaging and tracking at the push of a button!
work as usual
Almost no drift
solid as a rock
The scientists and developers at abberior understand the importance of smooth and simple operation when performing biological research. That’s why our MINFLUX system is built around a standard microscope body that provides a variety of options ranging from widefield fluorescence, DIC, phase contrast over confocal and STED, all the way up to MINFLUX. To maximize extendability, we built our MINFLUX system with reliable and time-tested elements assembled on a robust optical breadboard. We use rock-solid opto-mechanical building blocks that have been proven to function seamlessly in hundreds of abberior microscopes all around the world.
Moreover, in line with our design philosophy for top-of-the-line instruments, our MINFLUX systems are future-proof: they are designed to allow adaptations with the latest technologies available: performance in perpetuity.
When performing experiments with nanometer resolution, miniscule sample drifts and movements can compromise performance. That’s why our MINFLUX comes with active sub-nanometer stabilization technology. When MINFLUX imaging is performed, a fully automated stabilization system based on laser-illuminated fiducial markers keeps the sample perfectly still, with residual fluctuations < 1 nm in 3D.